| Human MUC1 Isoform Y Protein (LTP10047) |
| LTP10047 |
| 100ug |
|
$563 In stock |
| MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers. |
| Recombinant Human MUC1 Isoform Y Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Ser24-Gly158. |
| MUC1 Isoform Y |
| Human |
| P15941-7 |
| Ser24-Gly158 |
| The protein has a predicted MW of 41.38 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on the Tris-Bis PAGE result. |
| 0 |
| C-hFc |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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