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| Human MSR1 Protein (LTP10040) |
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| LTP10040 |
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| 100ug |
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$406 In stock |
| The macrophage scavenger receptor 1 (Msr1, also called SRA) is a pattern recognition receptor primarily expressed on myeloid cells, which plays an important role in the maintenance of immune homeostasis. Msr1 promotes the pathogenesis of virus-induced FH by enhancing induction of neutrophil NETosis and subsequent complement activation. Targeting Msr1 may be employed as a new immunotherapeutic strategy for FH. |
| Recombinant Human MSR1 Protein is expressed from Expi293 with His tag at the N-terminal. It contains Lys77-Leu451. |
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| MSR1 |
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| Human |
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| P21757-1 |
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| Lys77-Leu451 |
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| The protein has a predicted MW of 42.39 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on the Tris-Bis PAGE result. |
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| 0 |
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| N-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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