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| Human IL-17Rc Protein (LTP10291) |
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| LTP10291 |
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| 100ug |
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$473 In stock |
| IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer. |
| Recombinant Human IL-17Rc Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Leu21-Arg467. |
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| IL-17Rc |
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| Human |
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| NP_703190.2 |
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| Leu21-Arg467 |
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| The protein has a predicted MW of 76.2 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human IL-17A, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 60.6ng/ml determined by ELISA. See testing image for detail. |
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| C-hFc |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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