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| Human IL-17R alpha/CD217 Protein (LTP10243) |
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| LTP10243 |
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| 100ug |
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$316 In stock |
| Interleukin 17 (also known as CTLA?8) is a T cell?expressed pleotropic cytokine. IL?17 binds to IL?17 receptor (IL?17 R) which shares no homology with any known family of receptors. While the expression of IL?17 is restricted to activated T cells, the IL?17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL?17 R gene was localized to chromosome 22. |
| Recombinant Human IL-17R alpha/CD217 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Leu33-Trp320. |
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| IL-17R alpha/CD217 |
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| Human |
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| Q96F46-1 |
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| Leu33-Trp320 |
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| The protein has a predicted MW of 34.6 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human IL-17R alpha, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17A, His Tag with the EC50 of 0.15ug/ml determined by ELISA (QC Test). The affinity constant of 1.57 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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