Human CD42b/GP1BA Protein (LTP10222)

Product Name
Human CD42b/GP1BA Protein (LTP10222)
Catalog Number
LTP10222
Quantity
100ug
Price
$450 In stock
Background
Absence of the CD42 complex leads to the Bernard-Soulier syndrome (BSS), which is a bleeding disorder characterized by thrombocytopenia and giant platelets. So far, mutations have been found in the genes encoding CD42a, CD42b and CD42c in patients with BSS**.
Description
Recombinant Human CD42b/GP1BA Protein is expressed from Expi293 with His tag at the C-terminal. It contains His17-Leu531.
Target
CD42b/GP1BA
Species
Human
Gene/Protein ID
P07359
Exact Sequence
His17-Leu531
Molecular Weight
The protein has a predicted MW of 57.6 kDa. Due to glycosylation, the protein migrates to 110-115 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human CD42b, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 11.3ng/ml determined by ELISA. See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human CD42b/GP1BA Protein (LTP10222)
  • 5 Units in Stock
Ask a Question

$450.00

Add to Cart: