Human CD209/DC-SIGN Protein (LTP10513)

Product Name
Human CD209/DC-SIGN Protein (LTP10513)
Catalog Number
LTP10513
Quantity
100ug
Price
$473 In stock
Background
C-type lectin CD209/DC-SIGN and CD209L/L-SIGN proteins are distinct cell adhesion and pathogen recognition receptors that mediate cellular interactions and recognize a wide range of pathogens, including viruses such as SARS, SARS-CoV-2, bacteria, fungi and parasites. Pathogens exploit CD209 family proteins to promote infection and evade the immune recognition system.
Description
Recombinant Human CD209/DC-SIGN Protein is expressed from Expi293 with His tag at the N-terminal. It contains Gln59-Ala404.
Target
CD209/DC-SIGN
Species
Human
Gene/Protein ID
Q9NNX6-1
Exact Sequence
Gln59-Ala404
Molecular Weight
The protein has a predicted MW of 40.5 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on the Tris-Bis PAGE result.
Activity
The affinity constant of 0.12 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
N-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human CD209/DC-SIGN Protein (LTP10513)
  • 5 Units in Stock
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