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| Human 4-1BB Ligand/TNFSF9 Trimer Protein (LTP10727) |
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| LTP10727 |
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| 100ug |
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$473 In stock |
| The 4-1BBL is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. 4-1BB ligand (4-1BBL) is an inducible molecule present on several APC types, including B cells, macrophages and DCs.4-1BB:4-1BBL pathway seems to amplify the existing costimulatory signals, even if the engagement of 4-1BB in the presence of a strong TCR signaling can induce IL-2 production in a CD28-independent manner. |
| Recombinant Human 4-1BB Ligand/TNFSF9 Trimer Protein is expressed from Expi293 with monomeric hFc tag at the N-terminal. It contains Arg71-Glu254. |
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| 4-1BB Ligand/TNFSF9 Trimer |
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| Human |
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| P41273 |
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| Arg71-Glu254 |
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| The protein has a predicted MW of 84.3 kDa same as Tris-Bis PAGE result. |
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| Immobilized Human 4-1BB, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human 4-1BB Ligand Trimer, hFc Tag with the EC50 of 5.7ng/ml determined by ELISA. See testing image for detail. |
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| N-monomeric hFc |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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