Histone H4 (1-23) R3Me2s-GGK(Biotin)

H4R3 symmetric dimethylation is a defined arginine methylation state used to study PRMT-dependent histone signaling and modification-selective recognition. The H4 tail provides a compact model for testing how symmetric dimethylarginine changes chromatin-associated protein interactions.

• arginine methylation studies
• PRMT pathway research
• histone-reader binding
• epigenetic pull-down assays

Symmetric dimethylarginine is chemically distinct from H4R3Me2a and H4R3Me1. Maintain the exact methylation symmetry in comparative assays.

1. Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone Receptor