Histone H4 (1-23) R3Me2a-GGK(Biotin)

H4R3 asymmetric dimethylation is a PRMT1-associated histone modification implicated in transcriptional coactivation and can promote subsequent H4 acetylation. This peptide supplies the exact asymmetric dimethylarginine form in a biotinylated H4 context.

• PRMT1 coactivator studies
• H4R3Me2a reader binding
• histone modification crosstalk
• streptavidin pull-down assays

Asymmetric and symmetric dimethylation have identical nominal methyl counts but different chemical structures and biological recognition. They must remain separate catalog products.

1. Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone Receptor