Histone H4 (1-23) R3Me1-GGK(Biotin)

H4R3 monomethylation is an arginine methylation state linked to PRMT1-dependent regulation of histone H4 and transcriptional activation. This biotinylated H4(1-23) peptide provides a defined monomethyl-arginine ligand for chromatin reader, methyltransferase and coactivator studies.

• PRMT1 research
• H4R3 methylation studies
• chromatin reader binding
• streptavidin pull-downs

Arg3 monomethylation must be distinguished from asymmetric and symmetric dimethylation because these PTM states are recognized differently by enzymes and binding proteins.

1. Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone Receptor