Histone H4 (1-23) K20Me2-GGK(Biotin)-NH2

H4K20me2 is an abundant histone modification with an important role in DNA-damage signaling and recruitment of proteins that recognize methylated Lys20. The defined biotinylated H4 peptide provides a useful ligand for checkpoint and chromatin-reader studies.

• DNA-damage response research
• H4K20me2 reader binding
• checkpoint signaling studies
• epigenetic pull-down assays

LifeTein overview text mistakenly refers to H3 Lys20 in one sentence; the product sequence and specification correctly identify H4 Lys20. The LifeTein description follows the verified chemistry.

1. Di-methyl H4 Lysine 20 Targets the Checkpoint Protein Crb2 to Sites of DNA Damage