Histone H4 (1-23) K20Me1-GGK(Biotin)-NH2

H4K20me1 is a major cell-cycle-regulated histone mark associated with chromosome organization and genome stability. This H4(1-23) peptide places monomethylation specifically at Lys20 and includes a C-terminal biotin capture handle.

• H4K20 methylation studies
• cell-cycle chromatin research
• reader-protein binding
• streptavidin pull-down assays

The monomethylated state should be compared with matched K20Me2 and K20Me3 peptides because the three methylation states have distinct biological distributions and functions.

1. A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse