Histone H4 (1-20), PRMT7 Substrate, M1

Catalog Number
LT9075
Product NameHistone H4 (1-20), PRMT7 Substrate, M1
Product Quantity1 mg
SequenceSGRGKGGKGLGKGGAKRHRK-NH2
Molecular Weight1991.5
Purity≥95%
Scientific Background

Histone H4(1-20)-NH2 is a GRG-containing H4 N-terminal peptide used as a substrate for protein arginine methyltransferase 7 (PRMT7). PRMT7 is a type II arginine methyltransferase capable of generating symmetric dimethylarginine modifications, making this peptide useful for defined methyltransferase assays.

Research Applications
  • PRMT7 activity assays
  • arginine methylation research
  • histone methyltransferase kinetics
  • epigenetic inhibitor screening
Experimental Notes

The C-terminal amide is part of this product's exact chemical identity. It is distinct from the free-acid H4(1-20) acetylated series.

Selected References
  1. PRMT7, a New Protein Arginine Methyltransferase That Synthesizes Symmetric Dimethylarginine
  • 1 Units in Stock
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