Histone H4 (1-20) K8Ac

H4K8ac is a site-specific histone H4 acetylation mark linked to transcription-associated chromatin and bromodomain-mediated recognition. The short free peptide provides a defined substrate for histone deacetylase and binding assays.

• H4K8 acetylation studies
• HDAC/sirtuin assays
• bromodomain research
• histone-binding studies

The free H4(1-20) chemistry makes this distinct from K8Ac peptides carrying biotin or longer tail sequences.

1. Substrate Specificity and Kinetic Mechanism of the Sir2 Family of NAD+-Dependent Histone/Protein Deacetylases