Histone H3 (31-41)

Histone H3(31-41) is a compact peptide centered on Lys36. H3K36 methylation is associated with transcribed chromatin and participates in recruitment of proteins involved in chromatin organization and RNA processing.

• H3K36 methylation studies
• histone methyltransferase assays
• reader-domain binding
• epigenetic enzyme controls

The short sequence is useful where a minimal H3K36-centered substrate is preferred. Modification state and peptide length can influence enzyme kinetics and reader affinity.

1. Histone H3 lysine 36 methylation is associated with transcriptional elongation and recruits chromatin-regulatory proteins