Histone H3 (1-8)

Histone H3(1-8) is a short unmodified N-terminal H3 fragment containing Lys4, a major methylation site. It provides a compact reference substrate or ligand for studies focused on the earliest residues of the H3 tail.

• histone modification studies
• chromatin enzyme assays
• epigenetic reader studies
• modification-state controls

The fragment boundaries and modification state are part of the exact chemical identity. Use sequence-matched controls when comparing modification-dependent activity.

1. Selected histone/chromatin study