Histone H3 (1-21) K18Ac-GGK(Biotin)-NH2

H3K18ac is an acetylated histone H3 mark associated with transcriptional activity and p300/CBP-dependent chromatin regulation. This amidated biotinylated peptide provides a defined H3K18ac ligand for binding and enzyme studies.

• H3K18 acetylation studies
• p300/CBP research
• bromodomain binding
• streptavidin pull-down assays

The GGK(Biotin)-NH2 terminal chemistry is part of the exact product. It should not be merged with free-acid K18Ac constructs or other H3 acetylation sites.

1. Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation