Histone H3 (1-21) Cit17-GGK(Biotin)

Citrullination of H3 Arg17 by PADI4 converts the positively charged arginine side chain to citrulline and can antagonize CARM1-mediated arginine methylation, altering transcription-associated chromatin signaling.

• PADI4/PAD4 studies
• histone citrullination research
• CARM1 antagonism
• chromatin protein binding

Cit17 is a noncanonical residue and should not be represented as Arg17. The GGK(Biotin) extension enables pull-down formats while preserving the defined citrullination state.

1. Histone Deimination Antagonizes Arginine Methylation