Ghrelin, Human

Human ghrelin is a 28-residue peptide hormone whose Ser3 octanoylation is required for activation of the growth hormone secretagogue receptor. It regulates appetite, growth-hormone release, metabolism and gastrointestinal physiology.

• neuroendocrine signaling
• GPCR and hormone-receptor pharmacology
• metabolic and feeding studies
• reproductive or gastrointestinal research

Exact species, terminal amidation, disulfide connectivity and post-translational modifications such as ghrelin acylation define the reagent and can strongly alter biological activity.

1. Selected peer-reviewed publication