Product Name | FITC-LPETG |
Product Quantity | 5mg |
Catalog Number | 6149 |
Molecular Weight | 1018.09 |
Sequence | FITC-Ahx-LPETG, FITC–aminohexanoic acid–LPETG |
Purity | > 95% as determined by HPLC |
Fomula | C49H59N7O15S1 |
Cat. No | Product Name |
5467 | Biotin-Ahx-LPETGS-NH2 |
6142 | Biotin-Ahx-LPETGS-COOH |
5716 | Biotin-AALPETG*G, G* is 2-hydroxyacetic acid |
6271 | FITC-Ahx-LPETGS |
6272 | Rhodamine B-Ahx-LPETGS |
6148 | Biotin-Ahx-LPETG-NH2 |
5747 | Biotin-ALPETGG |
5989 | Cy5-Cys-HHHHHHHHHLPETGG |
35816 | VC-PAB-MMAE-LPETGG |
Product Description | Biotin, Ahx linker, amidation; The majority of Staphylococcus aureus virulence- and colonization-associated surface proteins contain a pentapeptide recognition motif (LPXTG). This motif can be recognized and cleaved by sortase A (SrtA) which is a membrane-bound transpeptidase. LPTEG-tagged probes and proteins can be conjugated using sortase A in a single step to glycines naturally exposed at the cell surface. |
Scientific Background | FITC-LPETG is a 5-residue synthetic peptide with the sequence Leu-Pro-Glu-Thr-Gly. FITC provides a fluorescent label for optical detection; an Ahx spacer separates the peptide from an attached label or affinity handle. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - fluorescence-based detection
- binding or localization assay development
- LC-MS/HPLC analytical method development
- sequence-specific assay controls
|
Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
Reference | Pasqual, G., Chudnovskiy, A., Tas, J. et al. Monitoring T cell–dendritic cell interactions in vivo by intercellular enzymatic labelling. Nature 553, 496–500 (2018). https://doi.org/10.1038/nature25442 |
