Factor Xa Substrate, Boc-IEGR-AMC

Boc-IEGR-AMC is a fluorogenic peptide substrate used for factor Xa and related trypsin-like coagulation proteases. Hydrolysis after arginine releases AMC fluorescence.

• protease activity assays
• MMP or serine-protease research
• coagulation and fibrinolysis studies
• enzyme inhibitor screening

Fluorophore, quencher, chromophore and terminal blocking groups are integral to exact reagent identity. Detection wavelengths and enzyme selectivity should be validated for each assay system.

1. Selected peer-reviewed publication