Erktide ERK2 Substrate, IPTTPITTTYFFFK

IPTTPITTTYFFFK is an alternative peptide substrate for ERK2 used in biochemical studies of MAP kinase catalysis. It contains multiple threonine residues and a tyrosine within a proline-rich phosphorylation context, providing a chemically distinct ERK2 substrate from ATGPLSPGPFGRR. The peptide is useful for substrate-comparison, catalytic and inhibitor studies involving ERK2.

• ERK2 kinase activity assays
• MAP kinase substrate comparison
• ERK catalytic mechanism studies
• kinase inhibitor screening

This reagent is chemically distinct from ATGPLSPGPFGRR ERKtide and should be treated as a separate substrate. Phosphorylation site distribution can depend on assay conditions and should be confirmed analytically when needed.

1. Catalytic Reaction Pathway for the Mitogen-Activated Protein Kinase ERK2