Endothelin-3, Human

Endothelin-3 is an endogenous 21-residue endothelin peptide with relatively strong ETB-receptor activity. It is used to study vascular, neural-crest, melanocyte and enteric nervous system signaling.

• cardiovascular and vascular signaling
• GPCR/receptor pharmacology
• endothelial and angiogenesis research
• peptide-processing studies

Disulfide connectivity, C-terminal amidation and exact precursor boundaries are integral to biological activity. Preserve the specified molecular form when comparing receptor or enzyme assays.

1. Selected peer-reviewed publication