|  | Cynomolgus CD27 Ligand/CD70 Protein (LTP10235) | 
    
    |  | LTP10235 | 
    
    |  | 100ug | 
    
    |  | 
    $473 In stock | 
 |  | CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. | 
|  | Recombinant Cynomolgus CD27 Ligand/CD70 Protein is expressed from Expi293 with His tag at the N-terminal. It contains Gln39-Pro194. | 
    
    |  | CD27 Ligand/CD70 | 
    
    |  | Cynomolgus | 
    
    |  | G7PYU6-1 | 
    
    
    |  | Gln39-Pro194 | 
    
    |  | The protein has a predicted MW of 18.4 kDa. Due to glycosylation, the protein migrates to 60-90 kDa based on the Tris-Bis PAGE result. | 
    
    |  | Immobilized Cynomolgus CD27 Ligand, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus/Rhesus macaque CD27, hFc Tag with the EC50 of 70.8ng/ml determined by ELISA. See testing image for detail. | 
    
    |  | N-His | 
    
    |  | Expi293 | 
    
    
    
    |  | > 95% as determined by Tris-Bis PAGE; | 
    
    |  | Less than 1EU per ug by the LAL method. | 
    
    |  | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. | 
    
    |  | Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. | 
    
    |  | Shipped at ambient temperature. | 
    
    |  | Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. | 
    
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