|
| Cynomolgus CD200 R1/CRTR2 Protein (LTP10133) |
|
| LTP10133 |
|
| 100ug |
|
|
$473 In stock |
| CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand. |
| Recombinant Cynomolgus CD200 R1/CRTR2 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Glu25-Leu267. |
|
| CD200 R1/CRTR2 |
|
| Cynomolgus |
|
| XP_005548207.1 |
|
| Glu25-Leu267 |
|
| The protein has a predicted MW of 28.09 kDa. Due to glycosylation, the protein migrates to 67-77 kDa based on the Tris-Bis PAGE result. |
|
| The affinity constant of 35.84 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
|
| C-His |
|
| Expi293 |
|
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
|
| Less than 1EU per ug by the LAL method. |
|
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
|
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
| Shipped at ambient temperature. |
|
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
|
|  |
