Cyclo(RGDfV) Integrin-Binding Peptide

Cyclo(RGDfV) is a classic cyclic RGD ligand that helped establish conformationally constrained peptides as high-affinity integrin antagonists. It is used in adhesion, angiogenesis and integrin structure-activity studies.

• integrin and cell-adhesion research
• ECM-receptor signaling
• biomaterials and conjugation studies
• cell targeting and migration research

Cyclization, D-amino-acid content, biotinylation and disulfide constraints are part of exact product identity and should be preserved when comparing biological activity.

1. Selected peer-reviewed literature