Cyclo(RGDfK) Integrin-Binding Peptide

Cyclo(RGDfK) is a conformationally constrained RGD ligand widely used to study αv-class integrins. Cyclization increases receptor affinity and proteolytic stability relative to many linear RGD peptides.

• integrin and cell-adhesion research
• ECM-receptor signaling
• biomaterials and conjugation studies
• cell targeting and migration research

Cyclization, D-amino-acid content, biotinylation and disulfide constraints are part of exact product identity and should be preserved when comparing biological activity.

1. Selected peer-reviewed literature