C-Type Natriuretic Peptide (CNP-22), Human

CNP-22 is the principal bioactive C-type natriuretic peptide and preferentially activates NPR-B/guanylyl cyclase-B. It regulates vascular tone, endothelial signaling and endochondral bone growth.

• cardiovascular and renal signaling
• natriuretic peptide receptor research
• GPCR or cyclic-GMP signaling
• vascular and smooth-muscle studies

Disulfide connectivity, amidation and exact peptide length define these vasoactive reagents. Maintain sequence- and modification-matched controls for receptor and signaling comparisons.

1. Selected peer-reviewed publication