CGRP beta, Human

Human beta-CGRP is a 37-residue calcitonin-gene-related peptide isoform encoded by CALCB. It is a potent vasodilatory neuropeptide and activates CLR/RAMP1 receptor complexes in cardiovascular and sensory signaling.

• calcitonin-family receptor pharmacology
• cardiovascular or metabolic signaling
• bone and calcium-homeostasis studies
• amyloid and aggregation research

N-terminal disulfide loops, C-terminal amidation, species sequence and analog substitutions are part of the exact molecular identity and can substantially change receptor activity or aggregation behavior.

1. Selected peer-reviewed publication