CGRP (8-37), Human beta

Human beta-CGRP(8-37) is a C-terminal receptor-binding fragment lacking the N-terminal activation region and is used as a competitive probe of CGRP receptor signaling.

• calcitonin-family receptor pharmacology
• cardiovascular or metabolic signaling
• bone and calcium-homeostasis studies
• amyloid and aggregation research

N-terminal disulfide loops, C-terminal amidation, species sequence and analog substitutions are part of the exact molecular identity and can substantially change receptor activity or aggregation behavior.

1. Selected peer-reviewed publication