Cathepsin D/E Substrate

This internally quenched peptide contains a hydrophobic cleavage region suitable for aspartyl proteases such as cathepsin D/E. Proteolysis separates Mca and Dnp reporter groups and increases fluorescence.

• protease activity assays
• MMP or serine-protease research
• coagulation and fibrinolysis studies
• enzyme inhibitor screening

Fluorophore, quencher, chromophore and terminal blocking groups are integral to exact reagent identity. Detection wavelengths and enzyme selectivity should be validated for each assay system.

1. Selected peer-reviewed publication