Caspase-2 Substrate, Ac-VDVAD-pNA

Ac-VDVAD-pNA is a chromogenic peptide substrate used to assess caspase-2-like activity. Cleavage of the VDVAD sequence liberates p-nitroaniline for quantitative absorbance measurements.

• caspase and apoptosis research
• protease activity assays
• inflammasome or cytotoxicity studies
• enzyme inhibitor profiling

Reporter group and terminal warhead are integral to reagent identity. AMC and pNA substrates require different detection modes, while aldehyde derivatives are inhibitors rather than turnover substrates.

1. Selected peer-reviewed publication