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| Biotinylated Human GUCY2C/Guanylyl cyclase C Protein (LTP10217) |
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| LTP10217 |
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| 100ug |
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$789 In stock |
| Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. |
| Recombinant Biotinylated Human GUCY2C/Guanylyl cyclase C Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Ser24-Gln430. |
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| GUCY2C/Guanylyl cyclase C |
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| Human |
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| P25092-1 |
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| Ser24-Gln430 |
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| The protein has a predicted MW of 48.8 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Anti-GUCY2C Antibody at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human GUCY2C, His Tag with the EC50 of 40.9ng/ml determined by ELISA. See testing image for detail. |
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| C-His-Avi |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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