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| Biotinylated Human GPRC5D Protein-VLP (LTP10646) |
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| LTP10646 |
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| 100ug |
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$2363 In stock |
| Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. |
| Recombinant Biotinylated Human GPRC5D Protein-VLP is expressed from Expi293. It contains Met1-Val345. |
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| GPRC5D |
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| Human |
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| Q9NZD1-1 |
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| Met1-Val345 |
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| The target protein has a predicted MW of 39.6 kDa. |
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| The affinity constant of 0.30 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
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| 0 |
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| Expi293 |
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| > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.Notice: If you need it for immunization, Do Not use any adjuvant. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening.Redissolve with distilled water to 100ul. |
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