[Beta-Ala70]-C3a (70-77)

[Beta-Ala70]-C3a (70-77) is a synthetic research peptide in the complement C3a-derived peptide family. Complement C3a is a 77-residue anaphylatoxin, and its C-terminal region contains important determinants of biological activity. Synthetic C3a(70-77), C3a(65-77), and related C-terminal analogs have been used to study C3a-like activity, receptor responses, immune modulation, and sequence-function relationships.

• C3a receptor and signaling studies
• complement peptide structure-activity experiments
• immune-cell response assays
• C-terminal fragment comparisons

The exact sequence, residue range, stereochemistry, cyclization, terminal state, species, and chemical modifications can materially affect activity. The supplied construct should be matched to the intended assay and the specific literature context.

1. Suppression of humoral immune responses by synthetic C3a peptides
2. Biological activity of synthetic C3a C-terminal oligopeptides