Catalog Number | LT8795 |
Product Name | Bactenecin, Bovine, Cyclic Peptide |
Product Quantity | 0.5 mg |
Sequence | RLCRIVVIRVCR; disulfide bridge Cys3-Cys11 |
CAS Number | 116229-36-8 |
Molecular Weight | 1484.0 |
Formula | C63H118N24O13S2 |
Purity | ≥95% |
Scientific Background | Bactenecin is a 12-residue cationic antimicrobial peptide from bovine neutrophils containing an intramolecular disulfide bond between Cys3 and Cys11. The resulting cyclic structure has been studied for its interactions with bacterial outer and cytoplasmic membranes and as a model for short host-defense peptides. Comparison with linear derivatives such as Bac2A is useful for examining the contribution of disulfide-constrained topology to antimicrobial function. |
Research Applications | - antimicrobial peptide assays
- bacterial membrane-interaction studies
- cyclic-versus-linear peptide comparisons
- bactenecin structure-activity research
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Experimental Notes | The Cys3-Cys11 disulfide is an essential structural feature of this product. Reduction or disulfide scrambling changes the molecular species and can alter activity. |
Selected References | - Interaction of the Cyclic Antimicrobial Cationic Peptide Bactenecin with the Outer and Cytoplasmic Membrane
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