[Arg6]-Beta-Amyloid (1-42), England Mutation

The H6R England mutation changes the Aβ N-terminal metal-binding region and has been studied for effects on peptide assembly. This Aβ42 form enables comparison of mutation effects across Aβ40 and Aβ42 backgrounds.

• familial Aβ mutation studies
• amyloid aggregation and oligomerization
• cerebral amyloid angiopathy research
• mutant versus wild-type comparisons

Mutation identity and Aβ length define this reagent. Compare with sequence-matched wild-type Aβ42 or the corresponding Aβ40 mutant under identical preparation conditions.

1. Selected familial amyloid mutation publication