[Arg6]-Beta-Amyloid (1-40), England Mutation

The H6R England variant is an N-terminal familial amyloid-beta mutation reported to accelerate oligomer formation and alter Aβ assembly relative to wild-type peptide.

• familial amyloid mutation studies
• Aβ aggregation and oligomerization
• Alzheimer disease research
• mutant versus wild-type comparisons

Mutation identity and Aβ C-terminal length are integral to this reagent. Compare with the sequence-matched wild-type Aβ40 or Aβ42 under identical preparation and aggregation conditions.

1. Selected mutation/amyloid study