Adrenomedullin (22-52), Human

Adrenomedullin(22-52) is a C-terminal human adrenomedullin fragment frequently used as an antagonist or competitive probe of adrenomedullin receptor signaling. It supports studies of vascular, endothelial and CLR/RAMP-mediated responses.

• cardiovascular and vascular signaling
• GPCR/receptor pharmacology
• endothelial and angiogenesis research
• peptide-processing studies

Disulfide connectivity, C-terminal amidation and exact precursor boundaries are integral to biological activity. Preserve the specified molecular form when comparing receptor or enzyme assays.

1. Selected peer-reviewed publication