Adrenomedullin (1-52), Human

Human adrenomedullin is a 52-residue amidated peptide containing an intramolecular disulfide ring. It is a potent vasodilator and regulates cardiovascular homeostasis, angiogenesis, endothelial barrier function and fluid balance through CLR/RAMP receptor complexes.

• cardiovascular and vascular signaling
• GPCR/receptor pharmacology
• endothelial and angiogenesis research
• peptide-processing studies

Disulfide connectivity, C-terminal amidation and exact precursor boundaries are integral to biological activity. Preserve the specified molecular form when comparing receptor or enzyme assays.

1. Selected peer-reviewed publication