Adipokinetic Hormone, G (AKH-G)

Adipokinetic Hormone, G (AKH-G) is a synthetic research peptide in the adipokinetic hormone (AKH) peptide family. Adipokinetic hormones are insect neuropeptides that mobilize stored energy reserves during metabolically demanding activities such as flight. AKH-family peptides act through cognate G-protein-coupled receptors, and species-specific AKH sequences have been characterized across insects. Comparative peptide/receptor studies are useful for examining ligand selectivity, energy-mobilization signaling, and structural diversity within the AKH/RPCH family.

• insect AKH receptor assays
• energy-mobilization studies
• species-specific peptide comparisons
• insect neuroendocrine research

The exact sequence, reporter group, phosphorylation state, stereochemistry, and terminal modifications should be considered when comparing this reagent with the parent peptide or published assay substrates. Enzyme concentration, buffer composition, cofactors, pH, ionic strength, and substrate concentration can also affect measured activity.

1. The adipokinetic hormones and their cognate receptor from the desert locust
2. Isolation and structure of a charged member of the RPCH-adipokinetic hormone peptide family