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Peptide Nucleic Acids (PNA): PNA Probes and Products 🧬

Peptide Nucleic Acids Peptide

Please click here to get a quote for Custom PNA Oligos now!

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Custom PNA synthesis 🧬: LifeTein provides custom PNA oligos, unlabeled (50nmole) or labeled (25nmol) by fluorescent dyes or other modifications. The PNA oligos can be conjugated to peptides for additional functionality. PNA oligomers can be labeled at 5' and/or 3' end. These labels are available upon request: fluorophores including FAM, FITC, Alexa Fluor dyes, Atto dyes, Cyanine dyes (cy3, cy5, cy7), QSY9, Pyrene, Dylight, quenchers (BHQ, Dabcyl), Acridine, Butyric acid, Alkyne (DBCO or Pentynoic acid), Azide, Biotin, photocleavable biotin, Maleimide, Myristol, Palmitic acid, et al. Contact us if your modification is not on the list.

Featured PNA Products


PMP01-25 Peptide nucleotide acid (PNA) PMP01-25: {GGCAAGTCTTCTTCGGA}-NH2   $499     $299, 125nmol,   In Stock
APP01-25 Peptide nucleotide acid (PNA) APP01-25: {GGCTCAACTCTGGACAG}-NH2   $499     $299, 125nmol,   In Stock

PNA FISH Probes


TelC telomere probee CCCTAACCCTAACCCTAA; Reverse Complementary Sequence (5' to 3'): TTAGGGTTAGGGTTAGGG
TelG telomere probe TTAGGGTTAGGGTTAGGG; Reverse Complementary Sequence (5' to 3'): CCCTAACCCTAACCCTAA
Pan-centromere CENPB probe ATTCGTTGGAAACGGGA; Reverse Complementary Sequence (5' to 3'): TCCCGTTTCCAACGAAT
Human only pan-centromere CENT probe AAACTAGACAGAAGCATT; Reverse Complementary Sequence (5' to 3'): AATGCTTCTGTCTAGTTT

Probe Ex (nm) Em (nm) MW Notes
Alexa 488 dye 490 525 699.7
FITC or FAM 495 519 389 pH sensitive
Cyanine Cy2 492 510
Cyanine Cy3 550 570
Alexa 555 dye 555 580 534.5
Rhodamine B 570 590
Abberior Star635 635 655 911 STED and Confocal Imaging
Cyanine Cy5 650 670
Silicon-Rhodamine (SiR) 652 674 472.61 Multicolour Live Cell Imaging

PNA FISH Probe

  • PNA has an electrically neutral backbone. This key feature of high specificity enables rapid hybridization with just a small amount of PNA probe without significant background signal. So PNA is very efficient and useful in applying to FISH (fluorescent in situ hybridization) at low concentrations.
  • C-rich probe (repeats of CCCTAA): TelC is a C-rich telomere probe for a leading strand (repeats of TAACCC).It is used to detect human, mouse, rat chromosomes.
  • G-rich probe (repeats of TTAGGG): TelG is a G-rich telomere probe for lagging strand (repeats of TTAGGG).
  • Pan-centromere probe: Cent probe is specific for human alpha satellite centromere and does not react to the mouse. The sequence of the probe is AAACTAGACAGAAGCAT.
  • CENPB probe: CENPB probe is a binding site for centromere protein B (CENP-B). The probe sequence is ATTCGTTGGAAACGGGA.
  • CAG repeat probes: (CAG)5-Cy3 and (CAG)5-Cy5

PNA Inhibitors


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