Z-LLE-AMC

Product Name:
 Proteasome Substrate II, Z-Leu-Leu-Glu-7-amido-4-methylcoumarin, Z-LLE-AMC
Sequence:
 Z-Leu-Leu-Glu-AMC, Z-Leu-Leu-Glu-7-amido-4-Methylcoumarin
Product Quantity:
 5 mg
Purity:
 >95%
Catalog Number:
 LTC-003
CAS Number:
 348086-66-8
Molecular Weight:
 664.8
Formula:
 C35H44N4O9
Product Description:
 Proteasome Substrate II, Z-LLE-AMC, is a fluorogenic substrate for the peptidylglutamyl-peptide hydrolyzing (caspase-like) activity of the proteasome. Z-LLE-AMC's Caspase-like activity can be quantified by fluorescent detection of free AMC (7-amino-4-methylcoumarin). AMC is excited at 340-360 nm and emits at 440-460 nm. Z-LLE-AMC can be stimulated in the presence of Mg2+ ions and rapidly inactivated by N-acetylimidazoleis.
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