Urotensin II-Related Peptide (URP), Human

Urotensin II-related peptide is an endogenous cyclic ligand of the UT receptor that contains the conserved CFWKYC pharmacophore of urotensin II. It is useful for defining UT-receptor activation and structure-activity relationships.

• cardiovascular and renal signaling
• natriuretic peptide receptor research
• GPCR or cyclic-GMP signaling
• vascular and smooth-muscle studies

Disulfide connectivity, amidation and exact peptide length define these vasoactive reagents. Maintain sequence- and modification-matched controls for receptor and signaling comparisons.

1. Selected peer-reviewed publication