Urotensin II, Human

Human urotensin II is a cyclic vasoactive peptide and endogenous agonist of the UT/GPR14 receptor. It is a potent vasoconstrictor in selected vascular beds and is studied in cardiovascular, renal and metabolic signaling.

• cardiovascular and renal signaling
• natriuretic peptide receptor research
• GPCR or cyclic-GMP signaling
• vascular and smooth-muscle studies

Disulfide connectivity, amidation and exact peptide length define these vasoactive reagents. Maintain sequence- and modification-matched controls for receptor and signaling comparisons.

1. Selected peer-reviewed publication