Description: This peptide corresponds to a specific region of the human beta-catenin protein, encompassing amino acids 764 to 809. beta-catenin is a crucial component of the Wnt signaling pathway, playing a significant role in cell-cell adhesion and gene transcription regulation.
Applications: The peptide is utilized in biochemical assays to study protein-protein interactions, particularly the binding dynamics between beta-catenin and other cellular partners. Understanding these interactions is vital for elucidating mechanisms underlying various cellular processes and diseases, including cancer.
Biological Importance: By isolating and examining this segment of beta-catenin, researchers can gain insights into its functional domains and interaction sites. This knowledge contributes to the broader understanding of signaling pathways and may aid in the development of therapeutic strategies targeting beta-catenin-related abnormalities.
The azide is available for different dye conjugation via click chemistry. For more detailed information, please refer to the article:https://doi.org/10.1016/j.isci.2021.102544 | 