Tau Peptide (422-441), Human

Tau(422-441) is a C-terminal human Tau fragment containing multiple serine residues and the region surrounding Ser422, a phosphorylation site associated with pathological Tau and neurofibrillary degeneration.

• neurodegeneration research
• protein aggregation and amyloid studies
• phosphorylation or epitope mapping
• inhibitor and antibody research

Residue boundaries and sequence identity are critical for Tau and alpha-synuclein fragment studies. Aggregation-sensitive peptides should be handled with consistent dissolution and incubation protocols.

1. Selected peer-reviewed publication