Substance P, FAM-Labeled

FAM-RPKPQQFFGLM-NH2 is fluorescently labeled Substance P, an amidated tachykinin neuropeptide involved in nociception, neurogenic inflammation and NK1-receptor signaling. The FAM tag enables fluorescence detection near 494/521 nm.

• NK1 receptor research
• neuropeptide trafficking
• pain and inflammation research
• fluorescence localization studies

The fluorescent label may alter receptor affinity or trafficking relative to native Substance P. Maintain the C-terminal amide because it is part of the biologically relevant Substance P structure.

1. Substance P and neurokinin 1 receptor: new insights into the pathophysiology and novel treatment opportunities