Somatostatin-14

Somatostatin-14 is a cyclic neuroendocrine peptide that inhibits growth hormone and numerous gastrointestinal and pancreatic secretions through somatostatin receptors. Its intramolecular disulfide bridge is essential to the native cyclic structure.

• neuroendocrine signaling
• GPCR and hormone-receptor pharmacology
• metabolic and feeding studies
• reproductive or gastrointestinal research

Exact species, terminal amidation, disulfide connectivity and post-translational modifications such as ghrelin acylation define the reagent and can strongly alter biological activity.

1. Selected peer-reviewed publication