Protegrin-1 (PG-1), Amide

Protegrin-1 is an 18-residue porcine cathelicidin with a disulfide-stabilized β-hairpin structure. Its broad antimicrobial activity depends strongly on the two native disulfide bonds and cationic surface.

• immunology and infectious-disease research
• T-cell or innate-immune assays
• host-pathogen interaction studies
• antimicrobial or antigen-presentation research

Exact sequence, HLA restriction, disulfide connectivity, spacer chemistry and fluorescent labeling define the reagent. Use sequence- and modification-matched controls in quantitative assays.

1. Selected peer-reviewed publication